Metabolic syndrome, metabolic syndrome components and thyroid nodule

Song Leng; Ying Liu; Hui Zhao; Guanghui Sun; Huiwen Liang

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Metabolic syndrome, metabolic syndrome components and thyroid nodule

VernacularTitle:代谢综合征及其组分与甲状腺结节相关性的研究
Author: Song LENG ; Ying LIU ; Hui ZHAO ; Guanghui SUN ; Huiwen LIANG
Publication Type:Journal Article
Keywords: Metabolic syndrome X; Thyroid nodules; Health management
From: Chinese Journal of Health Management 2011;05(4):211-214
CountryChina
Language:Chinese
Abstract: Objective To evaluate the relationship of metabolic syndrome (MS) and MS components with thyroid nodule. Methods A total of 10 357 subjects ( age ＞ 18 years old) who received physical checkup at the Second Affiliated Hospital of Dalian Medical University between June 2009 and June 2010 were enrolled in this retrospective study. Anthropometric parameter, fasting plasma glucose (FPG),serum lipid profile, blood uric acid, alanine aminotransferase and thyroid ultrasonography were measured. Results The prevalence of thyroid nodule,MS,and thyroid nodule + MS was 46. 96% ,23. 6%,and 11.6%, respectively. The prevalence of thyroid nodule was significantly higher in MS patients than in non MS patients ( 75.9% vs 38. 0%, P ＜ 0. 05 ). Multifactor logistic analysis showed that MS, body mass index (BMI) and FBG (β vales were 0. 78,1.22,and 0. 62,respectively; odds ratios were 4. 167,3. 876,and 2. 359, respectively; all P ＜ 0. 05 ) were independently correlated with the development of thyroid nodule. Conclusions Significantly increased prevalence of thyroid nodule could be found in MS patients. BMI and FBG may be independent risk factors of thyroid nodule.