Clinical value of video-EEG on adrenocorticotrophic hormone therapy for infantile spasms
10.3760/cma.j.issn.1673-4912.2011.04.011
- VernacularTitle:视频脑电图评估促肾上腺皮质激素治疗婴儿痉挛症的疗效
- Author:
Yan CHEN
;
Xinguo LU
;
Li CHEN
;
Weiyan CHEN
;
Yana XU
;
Yongli LI
;
Jianxiang LIAO
- Publication Type:Journal Article
- Keywords:
Adrenocorticotrophic hormone;
Infantile spasms;
Video-EEG;
Infant
- From:
Chinese Pediatric Emergency Medicine
2011;18(4):323-326
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyse the value of video-EEG (VEEG) in the infantile spasms (IS)children treated with adrenocorticotrophic hormone (ACTH). Methods The clinical data of 65 children with IS in our hospital from Jan 2005 to Dec 2009 were collected and the characteristics of VEEG were analyzed before and after treated with ACTH. Results All the 65 cases appeared hypsarrhythmia in the interphase before treated with ACTH. Cluster spasms and the characteristics of VEEG were recorded. After treated with ACTH,40 of 65 cases (61.5%) with epileptic seizure were controlled,in whom 27 cases (67.5% ,27/40)with hypsarrhythmia disappeared or improved obviously. The other 25 of 65 cases (38.5%) with epileptic seizure were uncontrolled,in whom only 5 cases (20. 0% ,5/25) with hypsarrhythmia disappeared. The rate of hypsarrhythmia disappeared or improved was significantly different between the epileptic seizure controlled and uncontrolled children (x2 = 13. 888, P ＜ 0. 000). Conclusion VEEG is not only important to make a definite diagnosis for IS,but also can provide an evidence in evaluating the effect of ACTH in IS children.
