Impulsive behavior in heroin addicts:a P00 ERP study
10.3760/cma.j.issn.1674-6554.2012.03.014
- VernacularTitle:海洛因成瘾者冲动行为的事件相关电位P300研究
- Author:
Bin LIN
;
Ruobing QIAN
;
Xianming FU
;
Wenfu HU
;
Tao YI
;
Chaoshi NIU
;
Yehan WANG
- Publication Type:Journal Article
- Keywords:
Heroin addiction;
Iowa gambling task;
Event-related potential;
P300;
Impulsive behavior
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2012;21(3):235-237
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the characteristic of P30o event-related potentials(ERP) of impulsive behavior in heroin addicts.Methods The Iowa gambling task (IGT) were performed by using the paradigm for psychological experiment both in heroin addiction group (HA group) and health control group (HC group),the inspection of electroencephalography were underwent in all the subjects concurrently.Following the collection of data of ERP,amplitude and latency of P300 were compared between the two groups,and then the relationship betweenamplitude or latency of P300 and the results of Barratt impulsiveness scale were analyzed separately.Results Compared to HC group,BIS score as well as the numbers of high frequency loss cards were significantly higher in HA group ( HA:75.12 ± 12.49,91.14 ± 21.35 ; HC:66.54 ± 8.61,73.71 ± 18.91 ; P ＜ 0.05 ),while the both two groups had visible waveforms of P30o,and the amplitude and latency were markedly lower ( HA:4.92 ± 1.14,293.43 ± 36.21 ; HC:7.65 ± 1.59,332.68 ± 40.15 ; P ＜ 0.05 ) and were negatively associated with BIS score in HA group( r =-0.76,-0.52,P＜ 0.05).Logistic regression results showed that the scores of BIS-11 were related to amplitude of P30o merely( P ＜ 0.05 ).Conclusion Impulsive behavior can be observed from the abnormal characteristic of the P300 event-related potential of impulsive behavior in heroin addicts,which may partly contribute to both addiction and relapse of heroin addict.
