Early hyperbaric oxygen treatment of diffuse axonal injury: a report of 45 cases

VernacularTitle:早期高压氧治疗脑弥漫性轴索损伤45例
Author: Chongguang WU ; Leiping WANG ; Jun YAO
Publication Type:Journal Article
Keywords: Diffuse axonal injury; Hyperbaric oxygen; Intracranial pressure; Prognosis
From: Chinese Journal of Trauma 2012;28(1):40-42
CountryChina
Language:Chinese
Abstract: Objective To explore the effect and mechanism of early hyperbaric oxygen in the treatment of patients with diffuse axonal injury ( DAI ). Methods A total of 45 cases of DAI were randomly divided into hyperbaric oxygen treatment group ( n =25 ) and normal treatment group ( n =20).The changes of intracranial pressure,Glasgow Comb Scale (GCS) and prognosis were observed.Results Compared with group treated with routine therapy,early intracranial pressure scores were reduced obviously,while GCS and prognosis were increased obviously in group treated with hyperbaric oxygen therapy ( P ＜ 0.05 ). Conclusion Early hyperbaric oxygen can significantly lower the level of intracranial pressure and improve the prognosis in the treatment of DAI patients.