Simultaneous pancreaticoduodenectomy and liver transplantation for hilar cholangiocarcinoma in one case
10.3969/j.issn.1673-8225.2011.31.045
- VernacularTitle:肝、胰头、十二指肠联合切除并肝移植治疗肝门部胆管癌1例
- Author:
Jianzhao HUANG
;
Wei FAN
;
Chengxian SHI
;
Xin GOU
;
Keli TANG
;
Ying ZHANG
;
Jun LIU
;
Peng YU
;
Yan LIU
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2011;15(31):5888-5890
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND: Because of the specificity and complexity of hepatic portal, carcinoma of bile duct of the hepatic portal is a difficulty in the surgical treatment. OBJECTIVE: To evaluate the safety and feasibility of simultaneous pancreaticoduodenectomy and liver transplantation for the end-stage hilar cholangiocarcinoma. RESULTS AND CONCLUSION: Pathology demonstrated a middle or low differentiation of hilar cholangiocarcinoma, and left, right hepatic duct, together with lobus quadratus were invaded. The tumor metastasized to hilar and posterior pancreatic lymphonodes, without involving the head of pancreas, duodenum and stomach. The function of transplanted liver recovered smoothly, and the endocrine and exocrine functions of pancreas were kept well. CA19-9 dropped to the normal levels. The patient recovered and discharged at 1 month after surgery, and still survived after one year follow up. These suggest that simultaneous pancreaticoduodenectomy and liver transplantation as a treatment of hilar cholangiocarcinoma are safe and feasible.