The influence of sulfentanil with various doses on the Bispectral index and Narcotrend index under the steady-state anestheaia of sevoflurane
- VernacularTitle:舒芬太尼在七氟醚稳态吸入下对BIS和Narcotrend值的影响
- Author:
Rongning WANG
;
Canlin SUN
;
Qulian GUO
- Publication Type:Journal Article
- Keywords:
Sevoflurane;
Sufentanil;
Depth of anesthesia;
Bispectral index;
Electroencephalography
- From:
The Journal of Clinical Anesthesiology
2010;(12):1017-1019
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of sulfentanil with various doses on the Bispectral index and Narcotrend index without nociceptive stimulus under the sevoflurane anesthesia.Methods Forty-eight ASA Ⅰ or Ⅱ patients undergoing gynecological operations were randomly divided into four groups（n=12）.All patients were induced with sevoflurane,the end-tidal concentrations of sevoflurane in all groups were adjusted to 1.0 MAC after tracheal intubation. Fifteen minutes later,sufentanil was injected in groups of B,C,D with the doses of 0.25,0.5,1.0 μg/kg respectively. The observations were finished when the values of Bispectral index and the Narcotrend index reached the minimum over 5 min. The values of Bispectral index and the Narcotrend index were recorded every minutes after the sufentanil injection. Results Among all groups,the BIS,Narcotrend values and tmax produced no statistical difference. Compared with the time when conscious lost,BIS and Narcotrend values were significantly lower when sevoflurane anesthesia reached steady state in all groups. The values of BIS and Narcotrend were significant lower after the injection of sufentanil in the groups of B,C and D（P0.05）. Conclusion Under the sevoflurane anesthesia with the steady end-tidal concentration of 1.0MAC,sufentanil could reduce the values of BIS and Narcotrend index without nociceptive stimulus without distinction among different doses.
