Adsorption of fentanyl in different materials of analgesia pump reservoir
- VernacularTitle:不同材质镇痛泵储药囊对枸橼酸芬太尼的吸附效应
- Author:
Hanzhong CAO
;
Xiaohong CHEN
- Publication Type:Journal Article
- Keywords:
Reservoir;
Fentanyl;
Adsorption;
Drug concentration
- From:
The Journal of Clinical Anesthesiology
2010;(12):1064-1065
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the adsorption of fentanyl by different materials of the analgesic pump reservoir. Methods The concentrations of fentanyl in pump reservoirs,which were made by different materials （glass,silica gel,polyvinyl chloride,non polyvinyl chloride） were detected with the time by high-performance liquid chromatography. The measurement was repeated three times.Results Fentanyl concentration in these reservoirs decreased with time,which decreased 6.3% in silica gel reservoir （P0.05）,2.7% in non polyvinyl chloride（P0.05）,1.5% in PVC and 1.2% in glass bottles.Conclusion Fentanyl citrate will be adsorbed by different materials of analgesia pump reservoir within 72 h,and the adsorption sequence was silica capsule,non polyvinyl chloride,polyvinyl chloride,and glass bottles.
