Effects of pudendal nerve stimulation with different frequency on bladder dysfunction in spinal cord injury dogs
10.3760/cma.j.issn.1000-6702.2012.09.013
- VernacularTitle:不同频率的阴部神经电刺激对骶上脊髓损伤犬神经源性膀胱功能障碍的影响
- Author:
Guoqing CHEN
;
Limin LIAO
;
Qian DONG
;
Yanhe JU
;
Juan WU
;
Wei LI
- Publication Type:Journal Article
- Keywords:
Bladder;
Spinal cord injury;
Pudendal nerve stimulation;
Dogs;
Urodynamics
- From:
Chinese Journal of Urology
2012;33(9):678-681
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the effects of pudendal ncrve stimulation with different frequency(5 Hz,20 Hz) on bladder dysfunction dogs after spinal cord injury.Methods The study was done in 4 dogs which chronic spinal cord transection at T9-T10 level.All the dogs underwent electrical stimulation of pudendal nerve (5 Hz,20 Hz).Then,bladder capacity,compliance,non-voiding contraction number (NVC) and voiding efficiency before and during stimulation were compared.Results The bladder capacity and the compliance was increased ( 58.9 ± 17.4) ％ and (53.1 ± 4.9 ) ％ ( P ＜ 0.05 ) by pudendal nerve stimulation with low frequency (5 Hz).Detrusor overactivity can be inhibited and the NVC decreased from 1.7 ± 1.3 to 0.9 ± 1.1.Pudendal nerve stimulation with medium frequency ( 20 Hz) can induce bladder contraction and increased voiding efficiency from (5.8 ± 1.0) ％ to ( 16.3 ± 2.6 ) ％ ( P ＜0.05).Conclusions Pudendal nerve stimulation with low frequency can inhibit detrusor overactivity and increase the bladder capacity and compliance in spinal cord injury dogs.Pudendal nerve stimulation with medium frequency can induce bladder contraction and increased voiding efficicncy.
