Progress of immune regulation mechanism of DN Treg cell on immunotherapy
10.3760/cma.j.issn.1673-4203.2012.11.017
- VernacularTitle:DN Treg细胞发挥免疫调节机制的研究进展
- Author:
Renbao YANG
;
Jiong CHEN
- Publication Type:Journal Article
- Keywords:
Immunomodulation;
Defense mechanisms;
Immunity,Cellular;
DN Treg cell
- From:
International Journal of Surgery
2012;39(11):777-780
- CountryChina
- Language:Chinese
-
Abstract:
Immune system is the autologous defence system to resist disease.αβ TCR+ CD3+ CD4-CD8-NK1.1-double negative T cell is a special T lymphocyte which has been described in both humans and rodent models.In recent years,the prognosis has been made in the mechanisms by which DN Treg target antigen-specific T cells and tumor cells.DN Treg cells play an important role in immune regulation,immunosuppression,autoimmune and resistance to the host reaction,HIV infection and antitumor.The study mainly introduces the advance of DN Treg cells in immune treatment.
