The association of insulin resistance and β-cell function with metabolic syndrome in T2DM
- VernacularTitle:2型糖尿病患者胰岛素抵抗和β细胞功能与代谢综合征的相关性
- Author:
Kun FANG
;
Xiaofeng LU
;
Xing JI
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2;
Insulin resistance;
Islet β-cell function;
Metabolic syndrome
- From:
Chinese Journal of Diabetes
2008;16(6):347-348
- CountryChina
- Language:Chinese
-
Abstract:
Objective To research the association of IR and β-cell function with MS in T2DM.Methods 116 T2DM subjects were divided into two groups:MS(n=60)and T2DM(n=56),and FIns,FPG,BP and other items were measured.Results HOMA-IR was significantly higher in MS than in T2DM and control group(P<0.05).HOMA-β was significantly lower in MS than in T2DM and control group(P<0.05).And FPG,waist circumference(WC)in MS group were positively correlated with the IR level(P<0.05).Conclusions The HOMA-IR was highest in T2DM with MS,and HOMA-β was lowest in T2DM with MS
