Analysis of the different levels of serum high sensitivity C-reactive protein and its related factors in subjects with isolated IGT or IFG
- VernacularTitle:单纯IGT和单纯IFG个体高敏C反应蛋白水平的差异及相关因素分析
- Author:
Lu GAO
;
Demin YU
- Publication Type:Journal Article
- Keywords:
Inflammation
- From:
Chinese Journal of Diabetes
2008;16(2):76-78
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the levels of serum high sensitivity C-reactive protein(hsC-RP) among subjects with normal fasting glucose plus normal glucose tolerance(NFG/NGT),IFG,IGT and IFG plus IGT,and to analyze the related risk factors. Methods 443 nondiabetic subjects aged 39-65 years were seperated into four groups:NFG plus NGT,IFG,IGT and IFG plus IGT.The serum hsC-RP levels and related factors were analyzed. Results Compared with IFG subjects,IGT subjects had higher hsC-RP levels.No differences in hsC-RP levels were found between NFG plus NGT group and IFG group, as well as between IGT group and IFG plus IGT group.Stepwise multiple regression showed that BMI and HOMA-IR were independent predictors of hsC-RP. Conclusions IGT subjects have significantly higher serum hsC-RP level than IFG subjetcts. The serum level of hsC-RP is associated with insulin resistance and the components numbers of metabolic syndrome.
