Efficacy of combination with medical therapy and behavior intervention on overactive bladder secondary to indwelling double J ureteral stent
10.3760/cma.j.issn.1000-6702.2012.09.018
- VernacularTitle:药物联合行为干预治疗输尿管留置双J管后膀胱过度活动症的疗效分析
- Author:
Zhaoxiang GUO
;
Runguo GU
- Publication Type:Journal Article
- Keywords:
Drug therapy,combination;
Behavior therapy;
Overactive bladder
- From:
Chinese Journal of Urology
2012;33(9):696-698
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the efficacy of combination medical therapy with behavior intervention on overactive bladder secondary to indwelling double J ureteral stent.Methods One hundred and seven OAB patients secondary to indwelling double J ureteral stent,with 48 males,59 females,age 27-58 (41 years old on average) were randomly divided into two groups.Group A were treated with the combination of medical therapy and behavior intervention.Group B were treated with only medical therapy.The regimen of medical therapy is tolterodine 2 mg,twice daily and alfuzosin 2.5 mg,three times daily.The patients were followed-up 1 month later and OABSS score was obtained.Results The OABSS urgency score was (3.5 ±0.9) and (0.9 ±0.2),the OABSS total score was (10.7 ±2.0) and (3.9 ±1.8),and QOL was (50.8 ± 15.9 ) and (28.9 ± 13.1 ) before and after the therapy in group A ( P ＜ 0.05 ),which showed great improvement after treatment.In group B,the urgency score was (3.4 ± 1.0) and ( 1.9 ± 0.5 ) and OABSS score was ( 10.6 ± 4.8 ) and (5.6 ± 1.7) before and after treatment,whose improvement is statistically significant ( P ＜ 0.05 ).The QOL score was ( 50.7 ± 16.1 ) and ( 39.9 ± 14.2 ) before and after treatment,whose improvement is not statistically significant (P ＞0.05).After the treatment,the difference of the improvement in urgency,total and the QOL scores between groups A and group B is statistically significant (P ＜ 0.05 ).Conclusions Tolterodine and alfuzosin can effectively alleviate overactive bladder symptoms secondary to indwelling double J ureteral stent by combining medical therapy with behavior intervention.
