Clinical observation of therapeutic efficacy of insulin sensitizer in treatment of newly-diagnosed type 2 diabetes
- VernacularTitle:罗格列酮和二甲双胍治疗新发2型糖尿病的疗效比较
- Author:
Shufang WANG
;
Xiaohong QU
;
Ying ZHAO
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2
- From:
Chinese Journal of Diabetes
2006;14(6):415-416
- CountryChina
- Language:Chinese
-
Abstract:
In observing the therapeutic efficacy of insulin sensitizer in treatment of early T2DM,120 T2DM patients were randomly divided into 3 groups: group A received 4 mg rosiglitazone daily;group B received 1.5 g metformin daily;group C received 4 mg rosiglitazone and 1.0 g met-formin every day.Before and after the treatment,fasting glucose,HbA1c,weight,adiponectin,BMI and HOMA-IR were measured or calculated.We found that fasting glucose,HbA1c and HOMA-IR of 3 groups were obviously decreased in comparison with their baseline and adiponectin was significantly increased.In conclusion,insulin sensitizer can obviously decrease the levels of glucose,HbA1c and HOMA-IR,and increase the level of serum adiponectin in T2DM.Insulin sensitizer in combination of metformin is suitable for treatment of T2DM.
