Effects of angiotensin Ⅱ on matrix metalloproteinase-2 (MMP-2) and tissue inhibitor of matrix metalloproteinase-2 (TIMP-2) mRNA expressions in rat mesangial cells
- VernacularTitle:血管紧张素Ⅱ对大鼠肾小球系膜细胞MMP-2和TIMP-2 mRNA表达的影响
- Author:
Ming LUO
;
Helin DING
;
Zuzhi FU
- Publication Type:Journal Article
- Keywords:
Tissue inhibitor of matrix metalloproteinase-2
- From:
Chinese Journal of Diabetes
2006;14(5):383-384
- CountryChina
- Language:Chinese
-
Abstract:
The study of glomerular mesangial cells of normal rats showed that angiotensin Ⅱ (ATⅡ) down-regulated the expression of MMP-2 mRNA, did not have significant effect on TIMP-2 mRNA. And in consequence, ATⅡ down-regulated the ratio of MMP-2 mRNA to TIMP-2 mRNA.
