The role of connexin 43 of heart tissues in experimental diabetic myocardial lesion
- VernacularTitle:实验性糖尿病心肌病变心肌连接蛋白43的意义
- Author:
Xiaoying XIA
;
Shenren CHEN
- Publication Type:Journal Article
- Keywords:
Immunohistochemistry
- From:
Chinese Journal of Diabetes
2006;14(4):288-289
- CountryChina
- Language:Chinese
-
Abstract:
The immunohistochemical staining showed the connexin 43 (Cx43) was strongly expressed (average gray value, AGV=230±5), distributed at junction area and intercalated disks of cardiocytes in normal rats,and much less expressed (AGV 193±4) (P<0.01) and distribution-disorganized in STZ-induced diabetic rats. This may be associated with the pathogenesis of diabetic myocardial lesions.