Correlation between the 95th nucleotide polymorphism of aldose reductase (AR) gene intron 8 and type 2 diabetic nephropathy
- VernacularTitle:醛糖还原酶基因内含子多态性与2型糖尿病肾病的相关性研究
- Author:
Yawen ZHANG
;
Demin YU
- Publication Type:Journal Article
- Keywords:
Gene polymor-phism
- From:
Chinese Journal of Diabetes
2005;13(6):446-447
- CountryChina
- Language:Chinese
-
Abstract:
The study on aldose reductase gene intron 8 A95 C polymorphismin 209 type 2 dia-betic patients and 84 healthy controls showed that the frequency of genotype AAis 7 %in DN,higherthan that in non-nephropathy (1 %) and control (1 %) ,suggsting that intron 8 genotype AA may be arisk factor for diabetic nephropathy .
