Parametric imaging for characterizing clear cell renal cell carcinoma with contrast-enhanced ultrasound
10.3760/cma.j.issn.1004-4477.2012.10.013
- VernacularTitle:肾透明细胞癌超声造影参数成像的应用研究
- Author:
Cuiju YAN
;
Beijian HUANG
;
Lijuan MAO
;
Liyun XUE
;
Feng MAO
;
Wenping WANG
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Microbubbles;
Kidney neoplasms;
Adenocarcinoma,clear cell
- From:
Chinese Journal of Ultrasonography
2012;21(10):872-875
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the features of quantitative analysis and parametric imaging of contrast-enhanced ultrasound (CEUS) in renal clear cell carcinoma (ccRCC).Methods Ninety-seven pathologically confirmed ccRCCs underwent conventional ultrasound and CEUS.Both quantitative parameters and dynamic vascular pattern (DVP) reconstructure were analyzed with Sonoliver software.Four types of DVP curves were described with type Ⅰ (Unipolar +),type Ⅱ (Bipolar + /-),type Ⅲ (Bipolar -/+) and type Ⅳ (Unipolar-),while the DVP parametric images,similarly,were divided into four types,with type Ⅰ,Ⅱ,Ⅲ and Ⅳ,respectively.Results As for the parameter of CEUS,there were statistical differences in maximum intensity (IMAX),area under the curve (AUC) and mean transit time (mTT) (P ＜0.05) and no statistic differences in rise time (RT) and time to peak (TTP) between ccRccs and peripheral renal parenchyma.Concerning of DVP of ccRCCs,type Ⅰ,Ⅱ,Ⅲ and Ⅳ accounted for 58.8％ (57/97),11.3％ (11/97),10.3％ (10/97) and 19.6％ (19/97) respectively.As for each type in DVP parametric images,the percentages were 58.8％ (57/97),11.3％ (11/97),8.2％ (8/97),21.7％ (21/97),respectively.Conclusions Quantitative analysis and parametric imaging can depict different features of vascularity in ccRCCs and improve the diagnosis of the tumors.
