Phospholipase A2 and Cancer
10.3760/cma.j.issn.1673-422X.2011.12.006
- VernacularTitle:磷脂酶A2与肿瘤
- Author:
Xia ZHANG
;
Jiejun WANG
- Publication Type:Journal Article
- Keywords:
Phospholipase A2;
Neoplasms
- From:
Journal of International Oncology
2011;38(12):897-900
- CountryChina
- Language:Chinese
-
Abstract:
Phospholipase A2 (PLA2) is consisted of a large group of enzymes,which can hydrolyze Sn-2 ester bond of the phospholipids and have different structures and functions.According to the latest related researches,many subtypes of PLA2 express abnormally in a various of tumors and have a close relationship with cancer proliferation,apoptosis,invasion,metastasis and prognosis.Different subtypes have different effects on neoplasms.PLA2 can supply a new insight on cancer therapy.
