Pilot study of acoustic radiation force impulse imaging for clinical pathological typing of advanced gastric cancer
10.3760/cma.j.issn.1004-4477.2011.12.010
- VernacularTitle:声辐射脉冲成像技术对进展期胃癌临床病理分型的初步研究
- Author:
Xueli ZHU
;
Pintong HUANG
;
Chao ZHANG
;
Yanjuan TAN
;
Ying TANG
;
Fuguang HUANG
;
Zhiqiang ZHENG
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Stomach neoplasms;
Neoplasms staging;
Acoustic radiation force impulse
- From:
Chinese Journal of Ultrasonography
2011;20(12):1040-1042
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the value of virtual touch tissue quantification (VTQ) in the evaluation of clinical pathological typing of advanced gastric cancer.MethodsFifty six patients who had been diagnosed as gastric cancer were examined using acoustic radiation force impulse.According to clinical pathological typing,all cases were divided into highly-moderately differentiated adenocarcinoma (14 cases) and non-highly-moderately differentiated adenocarcinoma (42 cases).A comparison with clinical pathologic results was made after surgery.The correlation of VTQ results and clinical pathological typing of gastric cancer was analyzed.ResultsThe VTQ value of highly-moderately differentiated adenocarcinoma was lower than that of non-highly-moderately differentiated adenocarcinoma [(1.49 ± 0.44) m/s vs (2.12 ± 0.45) m/s],with statistical significance( t =-4.53,P ＜0.05).According to the maximum area under the ROC curve,the cutoff value of VTQ was 1.795 m/s,the sensitivity and specificity were 78％ and 86％,respectively,the Youden's index was 0.64,and with high reproducibility(Kappa =0.81).ConclusionsVTQ could initial estimate the clinical pathological typing of advanced gastric cancer before operation.
