Fetal akinesia deformation sequence: an etiology of fetal multiple joint contractures with poor prognosis
10.3760/cma.j.issn.1004-4477.2011.12.018
- VernacularTitle:胎儿运动机能丧失变形序列:一种预后不良型胎儿多发关节挛缩畸形
- Author:
Liang WANG
;
Hua MENG
;
Yuxin JIANG
;
Qing DAI
;
Zhonghui XU
;
Meng YANG
;
Yan YUAN
;
Yunshu OUYANG
;
Yixiu ZHANG
;
Jia LU
;
Xiao YANG
- Publication Type:Journal Article
- Keywords:
Ultrasonography,prenatal;
Abnormalities,multiple;
Fetal akinesia deformation sequence
- From:
Chinese Journal of Ultrasonography
2011;20(12):1063-1065
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo evaluate the diagnostic capability of prenatal ultrasound in diagnosis of fetal akinesia deformation sequence (FADS).MethodsThe prenatal sonographic characteristics of 5 fetuses with FADS were analyzed retrospectively.ResultsBoth multiple joint contractures and central nervous system (CNS) anomalies,which include 5 small head circumferences,2 short cerebellar diameters,and 1 flat forehead,were found by prenatal ultrasound in all 5 FADS fetuses.Additional fetal abnormalities such as micrognathia,polyhydramnios,short umbilical cord and intrauterine growth retardation were also observed.The results of fetal chromosome analysis were available in 2 cases indicating normal karyotype.Conclusions Prenatal identification and diagnosis of FADS is possible based on the findings of sonographic examination.
