MRI findings and correlation with pathological features in breast phyllodes tumor
10.3760/cma.j.issn.1005-1201.2011.12.007
- VernacularTitle:乳腺叶状瘤的MRI表现及病理对照分析
- Author:
Xigang SHEN
;
Hongna TAN
;
Weijun PENG
;
Ruimin LI
;
Yajia GU
;
Da HUANG
;
Juan MAO
;
Liangping ZHOU
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Magnetic resonance imaging;
Comparative study
- From:
Chinese Journal of Radiology
2011;45(12):1108-1112
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo study the MR Imaging features of breast phyllodes tumor (PT),and to correlate it with pathological results.MethodClinical and MRI findings were retrospectively reviewed in twenty-seven women with 28 PTs lesions confirmed by surgical pathology.Statistical analyses were one-way ANOVA for size analysis,Fisher exact test for analysis of MR appearances and Spearman correlation to study the relationship between MRI findings and BI-RADS categories.Results( 1 ) The histologic findings were benign,borderline and malignant PTs in 14.3％ (4/28),53.6％ (15/28) and 32.1％ (9/28) of lesions,respectively.(2) The mean maximum-diameter were (6.4 ± 3.9) cm,(5.7 ± 2.2) cm in borderline type and (4.8 ± 1.8)cm in benign type respectively.The results showed differences in lesion's size among the three type (F = 287.541,P =0.000),especially between malignant and benign type (P = 0.033 ).(3)Internal non-enhanced septations and silt-like changes on enhanced images,as well as time-signal curve on MRI correlated significantly with the histological grade ( P ＜ 0.05 ).( 4 ) If the category BI-RADS ≥ 4a was considered to be a suspicious sign for malignant lesion,the diagnostic accuracy of MRI would be 96.4％ (27/28),and the BI-RADS category of the MRI could reflect the PT's histological grade with a low correlation coefficient ( r = 0.382,P = 0.045 ).Conclusion The findings of PT on MRI have some characteristics,with tumor size and several MRI features correlating with the histological grade of breast PT.
