Effects of pioglitazone on the expression of genes relative to differentiation and function of primary brown adipose tissue cells in mice with diet-induced obesity
10.3760/cma.j.issn.1000-6699.2011.11.020
- VernacularTitle:吡格列酮对肥胖小鼠原代棕色脂肪细胞分化和功能基因表达的影响
- Author:
Miao HU
;
Juan LIU
;
Long WANG
;
Guoxian DING
- Publication Type:Journal Article
- Keywords:
Pioglitazone;
Brown adipose tissue;
PPA Rγ′;
Uncoupling protein-1
- From:
Chinese Journal of Endocrinology and Metabolism
2011;27(11):947-949
- CountryChina
- Language:Chinese
-
Abstract:
The effect of pioglitazone on the expression of genes relative to differentiation and function of primary brown adipose tissue cells was detected for the new treatment of obesity and type 2 diabetes.The results showed that pioglitazone promoted the differentiation and function of brown adipocytes( P<0.05 ).