Surgical treatment of hepatocellular cancer with hypersplenism
10.3760/cma.j.issn.1007-8118.2011.12.010
- VernacularTitle:合并脾功能亢进肝癌患者的外科治疗
- Author:
Xielin FENG
;
Junping PENG
;
Yong HU
;
Aixiang LIU
;
Hui ZHANG
;
Lang TIAN
- Publication Type:Journal Article
- Keywords:
Hepatocellular cancer;
Hypersplenism;
Hepatectomy;
Splenectomy
- From:
Chinese Journal of Hepatobiliary Surgery
2011;17(12):986-988
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the efficacy of liver cancer resection combined with splenectomy for patients with hepatocellular carcinoma with hypersplenism.Methods Among 35 patients with hepatocellular cancer and hypersplenism treated from March 2004 to January 2006 at our hospital,12 patients accepted simultaneous liver cancer resection and splenectomy (the splenectomy group)and 23 only accepted liver cancer resection (the non-splenectomy group).The liver function,platelets and white blood cells were analyzed retrospectively.Results All the operations were successfully carried out.Within 1 week after operation,the white blood cell count increased from (3.2 ± 1.7) × 109/L to (8.5±-5.3) × 109/L,the platelet count increased from (52.6±23.7) × 109/L to (245.3±94.6) ×109/L(P＜0.01) in the group of patients with combined splenectomy,while little change occurred in the non-splenectomy group.The liver function in the splenectomy group recovered to the preoperational value within 1 week.Two years after operation,7 (58.3％) patients were still surviving in the splenectomy group and the mean tumor-free survival was (16.4 ± 4.3) months compared with (14.3 ±5.2) months in 10 (43.5％) patients in the non-splenectomy group,(P＜0.005).Conclusion Liver cancer resection combined with splenectomy was efficacious to hepatocellular cancer with hypersplenism.
