Heparanase accelerates angiogenesis after cerebral ischemia
10.3760/cma.j.issn.1673-4165.2011.11.013
- VernacularTitle:乙酰肝素酶促进脑缺血后血管发生
- Author:
Yanyu XUE
;
Jimei LI
;
Jinmei SUN
;
Yongbo ZHANG
- Publication Type:Journal Article
- Keywords:
Heparanase;
Glycoside hydrolases;
Heparitin sulfate;
Neovascularization,pathologic;
Brain ischemia
- From:
International Journal of Cerebrovascular Diseases
2011;19(11):864-866
- CountryChina
- Language:Chinese
-
Abstract:
Heparanase (Hpa) is the only β-D-glucuronidase of degading heparan sulfate proteoglycans in the body of mammalian.Studies have confirmed that Hpa accelerates angiogenesis in multiple physiopathological processes; however there are still a few studies about the expression and role of Hpa after cerebral ischemia.This article mainly introduces the relation between Hpa and angiogenesis after cerebral ischemia.
