The role of dendritic cells in atherosclerosis
10.3760/cma.j.issn.1673-4165.2011.11.014
- VernacularTitle:树突状细胞在动脉粥样硬化中的作用
- Author:
Peng LIU
;
Yajie LIU
;
Shaohui CHEN
- Publication Type:Journal Article
- Keywords:
Dendritic cells;
Inflammation;
Atherosclerosis;
Carotid artery diseases;
Intracranial arteriosclerosis
- From:
International Journal of Cerebrovascular Diseases
2011;19(11):867-871
- CountryChina
- Language:Chinese
-
Abstract:
Both basic and clinical studies have confirmed that inflammatory response plays an important role in the occurrence and development of atherosclerosis (AS) as well as its caused clinical events.The aggregation phenomena of T lymphocytes,macrophages and dendritic cells (DCs) can be observed in intima and atherosclerotic plaques in the event of atherosclerosis.As the most important antigen-presenting cells activating T lymphocytes,DCs have the important functions of determining T lymphocyte activation,apoptosis,and aggregation.This article reviews the correlation between DCs and atherosclerotic lesions.
