Renal Behcet's disease: a report of one case, with literature review

VernacularTitle:临床病例评析——口腔溃疡生殖器溃疡血尿蛋白尿
Author: Fangxiao ZHU ; Yunzhen SHI ; Xiao ZHANG ; Yunxia LEI ; Shuangxin LIU ; Ping MEI
Publication Type:Journal Article
Keywords: Behcet syndrome; Kidney diseases; Pathology,clinical
From: Chinese Journal of Rheumatology 2011;15(12):821-824
CountryChina
Language:Chinese
Abstract: Objective To analyze the clinical features of renal involvement associated with Behcet's disease (BD) through 1 case and to make a review of the literature in order to early diagnose and cure in time,thus decrease misdiagnosis and mistreatment.Methods This is a retrospective study.The case was diagnosed with BD and the renal damage was confirmed by renal biopsy.The clinical features and histology features were analyzed.Results The presentation of renal disease was edema,proteinuria and microscopic hematuria.The clinical spectrum of renal BD showed a wide variation.Amyloidosis (AA type),GN (nephritis),and microscopic vascular disease were the main causes of renal BD.Patients with vascular involvement had a high risk of amyloidosis and amyloidosis was the most common cause of renal failure in BD.Conclusion Kidney is one of the organs that can alter the prognosis of the BD,so the screening for renal damage must be done for each patient with this disease.Routine urine analysis and measurement of serum creatinine level are needed for early diagnosis of renal BD.Immunosuppressive drugs can be useful in selected cases.