Clinical analysis on the diabetic nephropathy patients with hypothyroidism
10.3760/cma.j.issn.1008-6315.2011.12.025
- VernacularTitle:糖尿病肾病合并甲状腺功能低下临床分析
- Author:
Xiangju LONG
- Publication Type:Journal Article
- Keywords:
Diabetic nephropathy;
Hypothyroidism;
Renal function;
Hemadialysis
- From:
Clinical Medicine of China
2011;27(12):1292-1294
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between hypothyroidism condition and renal function in diabetic nephropathy (DN) patients via measuring the hypothyroidism status of patients at different renal function stages of DN.Meanwhile,the influence of hemadialysis on thyroid function was also evaluated to pursue better treatment measures for the patients with diabetic nephropathy complicated with hypothyroidism.Observe the influence of hemadialysis in values of thyroid function,and discuss the better therapy of diabetic nephropathy with hypothyroidism.Methods FT3,FrT4,TSH3 were tested by chemiluminescence immunoassay in 125 cases of DN for January 2008 to December 2010,and SCr、BUN were tested at the same time.Then investagated the changes of thyroid function items of DN with uremia patients after hemadialysis.Analyze the data statistically.Results SCr,BUN of DN group were negatively co-related to FT3,FrT4 ( r =- 0.65,- 0.46,-0.76,- 0.56,P ＜ 0.05 ) ; But not co-related to TSH3 ( P ＞ 0.05 ).The changes of thyroid function items,namely FT3,FrT4,TSH3 of DN with uremia patients after hemadialysis was not statistically significant.Conclusion SCr,BUN were negatively correlated to FT3,FrT4,but there was no relation between SCr,BUN and TSH3.Hemadialysis therapy is not beneficial for the hypothyroidism in DN patients.
