Advances in clinical research on autoimmune pancreatitis
10.3760/cma.j.issn.1007-8118.2011.12.026
- VernacularTitle:自身免疫性胰腺炎临床研究进展
- Author:
Lei XIN
;
Yang GAO
;
Zhaoshen LI
- Publication Type:Journal Article
- Keywords:
Autoimmune pancreatitis;
Diagnostic criteria;
Differential diagnosis
- From:
Chinese Journal of Hepatobiliary Surgery
2011;17(12):1029-1032
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,research on autoimmune pancreatitis (AIP) has gained significant progress.AIP is a special type of chronic pancreatitis which is mediated by an autoimmune mechanism.It is characterized by the infiltration of lymphocytes and plasma cells leading to pancreatic fibrosis and dysfunction.AIP can affect the bile ducts,salivary glands,kidneys and other organs outside the pancreas.The common manifestations include obstructive jaundice,abdominal pain,and weight loss,which are similar to pancreatic cancer.Steroid therapy is of significant effect.There is no consensus nowadays on the diagnostic criteria of AIP across the world.There are many studies on the pathological subtypes,imaging,serological markers and biopsy techniques on AIP,and research focuses on the differential diagnosis from pancreatic cancer.
