MRI diagnosis of aggressive fibromatosis
10.3760/cma.j.issn.1005-1201.2011.12.020
- VernacularTitle:侵袭性纤维瘤病的MRI诊断
- Author:
Yunyan ZHANG
;
Yajia GU
;
Weijun PENG
;
Jian WANG
- Publication Type:Journal Article
- Keywords:
Fibromatosis;
aggressive;
Magnetic resonanceimaging;
Pathology;
clinical
- From:
Chinese Journal of Radiology
2011;45(12):1155-1158
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo analyze the MRI features of aggressive fibromatosis (AF) in order to improve its diagnostic accuracy.Method The clinical files and MRI appearances of 66 AF patients (primary 19 cases,recurrent 47 cases) were reviewed and compared with the postoperative pathological findings.ResultsThe median age of all patients was 31 years( range,11—60 years) with a male-to-female sex ratio of 1 ∶ 3.4.Eighty tumors were discovered.There were 5 superficial fibromatosis and 75 deep fibromatosis in which 2 lesions were intraabdominal,6 lesions in the abdominal wall and 67 lesions extraabdominal.The average long diameter of all lesions was ( 8.7 ± 5.4 ) cm,of superficial lesions ( 5.7 ±2.8) cm,of deep lesions ( 8.9 ± 5.5 ) cm.Of the 80 tumors,79 were displayed as space-occupying intramuscular lesions; 47(58.8% ) were ovoid or lobulated and 22( 27.5% ) were infiltrative in shape; 48 (60%) lesions had a well-defined margin,of which 4 formed a pseudocapsule as they enlarged by compressing normal tissue.To compare with the muscle signal intensity on MRI,75 lesions demonstrated isointensity,mild hyperintensity or hypointensity on T1 WI,heterogeneous high intensity on T2 WI,and avid heterogeneous enhancement after contrast administration.There was no necrosis or surrounding edema in all lesions.Tumors destroyed bone in 2 cases.ConclusionAggressive fibromatosis has characteristic features on MRI,and MRI is valuable in diagnosising AF and evaluating the extend of lesion and involvement of adjacent structures.