A Case of Intravascular Large B Cell Lymphoma.
- Author:
Chang Sik KIM
1
;
Yong Tae PARK
;
Tae Ho PARK
;
Jae Hak YOO
;
Kea Jeung KIM
Author Information
1. Department of Dermatology, Kangbuk Samsung Hospital, School of Medicine, Sungkyunkwan University, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Large B cell lymphoma;
Intravascular
- MeSH:
Adult;
Arm;
Biopsy;
Central Nervous System;
Humans;
Lymphocytes;
Lymphoma;
Lymphoma, B-Cell*;
Skin;
Thigh
- From:Korean Journal of Dermatology
2004;42(2):223-225
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Intravascular large cell lymphoma (angiotropic large cell lymphoma) is a rare, multifocal, intravascular neoplasm of lymphoid cells that preferentially involves the vasculature of the skin and central nervous system. We report a 33-year-old man who had asymptomatic purpuric patches on both thighs, left arm, and left flank. A biopsy specimen showed intravascular collections of tumor cells with irregular nuclear contour and prominent nucleoli. These cells were positive for CD45, CD20, but negative for CD3, and CD56. The clinicopathologic features and immunohistochemical profiles were diagnostic of intravasculr large B cell lymphoma.
