The role of connexin in lung diseases
10.3760/cma.j.issn.1673-4408.2011.06.006
- VernacularTitle:间隙连接蛋白与肺部疾病的研究进展
- Author:
Chong LI
;
Hongyu LIU
;
Jianhua FU
- Publication Type:Journal Article
- Keywords:
Connexins;
Gap junction;
Lung diseases
- From:
International Journal of Pediatrics
2011;38(6):545-548
- CountryChina
- Language:Chinese
-
Abstract:
As a cell membrane protein of human body,connexins are closely related to the cell metabolism,proliferation and differentiation,which are highly expressed in lung.Recent studies have shown that connexins play an important role in the lung diseases,such as pulmonary fibrosis,lung injury,lung tumors and so on.This review is to summarize the characteristics of connexins molecules,biological function,the distribution in the lung tissues,as well as the possible regulation mechanisms in the lung diseases.
