Progress of asthma and Th17 cells
10.3760/cma.j.issn.1673-4408.2011.06.016
- VernacularTitle:Th17细胞与哮喘的研究进展
- Author:
Yanyan HU
;
Yating WANG
- Publication Type:Journal Article
- Keywords:
Bronchial asthma;
Th17 cells;
Interleukin-17
- From:
International Journal of Pediatrics
2011;38(6):579-582
- CountryChina
- Language:Chinese
-
Abstract:
Bronchial asthma is a chronic inflammation airway disease.The imbalance of T helper cell (Th) 1/Th2 immunity plays an important role in the pathogenesis of allergic asthma.Recent years a new T cell lineage has been recognized as Thl7 cells because they can produce cytokines interleukin-17.The new studies find that interleukin-17 is a negative regulator of asthma,and interleukin-17 or Th17 cells may represent an interesting therapeutic target in asthma.