Therapeutic value and heterogeneity of zinc supplementation for treating diarrhea in children
10.3760/cma.j.issn.1673-4408.2011.06.020
- VernacularTitle:锌对儿童腹泻的治疗价值与差异
- Author:
Junming LUO
;
Ruping LUO
- Publication Type:Journal Article
- Keywords:
Zinc therapy;
Diarrhea;
Heterogeneity;
Children
- From:
International Journal of Pediatrics
2011;38(6):592-594
- CountryChina
- Language:Chinese
-
Abstract:
Zinc supplementation can reduce the mean duration,the recurrence rate and mortality of diarrhea.Nonetheless,it has no effect on stool frequency or stool output.Zinc supplementation results in different effort for the difference of the duration of diarrhea,pathogens,zinc type and doses of zinc,and shows no effect in infants younger than 6 months.Using iron as a co-intervention can reduce the effect of zinc,but vitamin A or ORS have a synergistic effect with the meeting.Average baseline zinc levels did not contribute to variations in the effect size.Zinc supplements are unlikely to improve compliance with the treatment for diarrheal disease.Longer course,zinc alone,malnutrition,diarrhea,breast-feeding children are prone to vomiting after oral administration of zinc.