Change of blood brain barrier permeability and mechanisms after cerebral hypoxia-ischemia
10.3760/cma.j.issn.1673-4408.2011.06.028
- VernacularTitle:脑缺氧缺血后血脑屏障通透性改变及其机制研究进展
- Author:
Bo WANG
;
Jiali XU
- Publication Type:Journal Article
- Keywords:
Hypoxia-ischemia;
Blood brain barrier;
Permeability
- From:
International Journal of Pediatrics
2011;38(6):620-623
- CountryChina
- Language:Chinese
-
Abstract:
The blood brain barrier(BBB) is a barrier system between the blood and brain tissue,which can maintain relatively stable of internal environment in the central nervous system (CNS).Cerebral hypoxiaischemia and other conditions can lead to the change of the permeability of BBB.This paper reviews the latest research for the structural basis and function of BBB,and for the scope,time and mechanism of the change of BBB structure and function during hypoxic-ischemic brain injury.This theory in the regulation of BBB may play an important role in the treatment of hypoxic-ischemic brain injury and underlying diseases of CNS.
