Effects of high mechanical index ultrasound of radiation microbubble on the colon cancer cell skeletal
10.3760/cma.j.issn.1004-4477.2011.11.026
- VernacularTitle:高机械指数超声辐照微泡对结肠癌细胞骨架的影响
- Author:
Hua ZHONG
;
Rui LI
;
Yanli GUO
;
Xing HUA
;
Xiaohang ZHANG
;
Yafang XUE
;
Zhaohui CHEN
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Microbubbles;
Colonic neoplasms;
Lovo cell;
Cytoskeleton
- From:
Chinese Journal of Ultrasonography
2011;20(11):996-999
- CountryChina
- Language:Chinese
-
Abstract:
Objective To Study the effects of high mechanical index ultrasound radiation microbubble on colon cancer cell skeletal.Methods Lovo cell were cultured in vitro,and this study was divided into control group,simple contrast agent group,microbubble plus ultrasound radiation group and simple ultrasound radiation group.Ultrasound contrast agent SonoVue and ultransound (frequency 1.5 MHz and MI 1.7) were used.Results In the control group,the microtubes were densest in dyeing silk,and extended to the edge of a cell.In the ultrasound and microbubble group,the microtubes were weaker and thin,the.network was mainly in the structure of the long axis.The cells arranged in a slight pigmentation to the density cell,to reach out many fine short hair,there were obviously a sense of silk and directional.In the microbubble and ultrasound group,Lovo cells streamed of the central significantly reduced,fluorescent lighting,with short hair.There was no difference in the ultrasound group and the microbubble group with microfilament and microtubule.Conclusions High mechanical index ultrasound radiation can changed into vacant,a trace of the assembly and distributed to the tumor cells are attacking,the transfer of restraining.
