Relationship of Tim-1 gene polymorphisms and disease
10.3760/cma.j.issn.1673-4408.2011.06.023
- VernacularTitle:Tim-1基因多态性与疾病的关系
- Author:
Zhiying HUANG
;
Baojin CHENG
- Publication Type:Journal Article
- Keywords:
T cell immunoglobulin domain and mucin domain protein;
Gene polymorphism;
Allergic diseases;
Autoimmune diseases
- From:
International Journal of Pediatrics
2011;38(6):602-605
- CountryChina
- Language:Chinese
-
Abstract:
As an important member of Tim gene family,T cell immunoglobulin domain and mucin domain protein (Tim) - 1 mainly expressed in T cell surface and adjust T cells immune response.Recent studies have found that Tim-1 gene polymorphisms may be linked with allergic diseases,autoimmune diseases and infection diseases.The review of relationship between Tim-1 polymorphism and diseases will have profound and long-term impact to expound the pathogenesis,providing new method to prevent and treat diseases.
