Study on the clinical efficacy of biapenem in treatment of hepatic failure complicated with bacterial infection
10.3760/cma.j.issn.1008-6706.2011.23.009
- VernacularTitle:比阿培南治疗肝衰竭并发细菌感染疗效观察
- Author:
Xiaodong GAI
;
Chen TAO
;
Jianxia DU
- Publication Type:Journal Article
- Keywords:
Hepatic failure;
Bacterial infection;
Biapenem
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(23):3185-3186
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical efficacy of biapenem treatment of in hepatic failure complicated with bacterial infection.Methods 30 patients with hepatic failure complicated with bacterial infection were randomly divided into two groups.Treatment group were administered biapenem(Zhengda Tianqing Pharmaceuticals)0.6g/d,while the control group were administered cefopergone sodium tazobactam sodium for Injection(Qili Haikou Pharmaceuticals)4.0g/d for one week.Results There were significan differences in the curative rate and effective rate of biapenem and cefopergone sodium tazobactam sodium,which were 86.67％ 73.33％ and 53.33％ 、33.33％respeitively(P＜0.05).Conclusion Biapenem in treatment of hepatic failure complicated with bacterial infections was effective against infection with mild adverse reactions.
