Effect of different doses atorvastatin on heart function in acute ST - segment elevation myocardial infarction
10.3760/cma.j.issn.1008-6706.2011.24.013
- VernacularTitle:不同剂量阿托伐他汀对急性ST段抬高心肌梗死患者心功能的影响
- Author:
Ruimei HAN
- Publication Type:Journal Article
- Keywords:
Myocardial infarction;
Acute;
Atorvastatin;
Brain natriuretic peptide
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(24):3340-3341
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo discuss the impact of different dosage of atorvastatins on heart function in acute STEMI.Methods136 STEMI patients were assigned into three groups with different doses atorvastatin.LVEF,CI,LVED,WMS and BNP were compared after treatment.ResultsThere were significant changes in LVEF,CI,WMS after treatment compared with pre-treatment( all P ＜ 0.05).LVEF,CI and WMS in group Ⅲ were significantly higher than group Ⅰ ( all P ＜ 0.05 ).BNP was significantly decreased in group Ⅲ compare with others ( all P ＜ 0.01 ).ConclusionAtorvastatin could improve heart function of STEMI.High dose(40mg qd) is more effective.
