The protective effect of Nimodipine treatment of brain damage in patients with cerebral hemorrhage

VernacularTitle:尼莫地平对脑出血后脑损害的保护作用研究
Author: Mingqing JIANG
Publication Type:Journal Article
Keywords: Cerebral hemorrhage; Brain injures; Nimodipine
From: Chinese Journal of Primary Medicine and Pharmacy 2011;18(23):3208-3209
CountryChina
Language:Chinese
Abstract: Objective To study the protective effect of Nimodipine treatment of brain damage in patients with cerebral hemorrhage.Methods 62 cases of brain damage in patients with cerebral hemorrhage were divided into treatment group and control group,each for 31 cases.The control group were given conventional treatment,and the treatment group were given Nimodipine on the basis of the control group,treatment for 10d.NIHSS,hematoma volume and clinical effective rate were compared.Results After treatment,the NIHSS was lower between two groups,the treatment group decline was more obvious(P ＜ 0.05).The hematoma volume was decreased,the treatment group decrease was more obvious(P ＜0.05).The total effective rate was 51.6％ in the control group,and the total effective rate was 77.4％.There were significantly statistical differences between two groups(P ＜ 0.05).Conclusion Nimodipine had a protective effect for brain damage in patients with cerebral hemorrhage,and could improve the nervous function and decrease hematoma volume,and it was a reliable drug.