Clinical therapeutic effects of solifenacin succinate in the treatment of overactive bladder symptom after benign prostatic hyperplasia operation
10.3760/cma.j.issn.0254-9026.2011.11.009
- VernacularTitle:琥珀酸索利那新治疗良性前列腺增生术后膀胱过度活动症的临床疗效观察
- Author:
Jianping LAI
;
Xuhui WAN
;
Guanghua FU
;
Daoju GAN
;
Xingbin LI
;
Pengfei GUO
;
Jian LI
- Publication Type:Journal Article
- Keywords:
Prostatectomy;
Urinary bladder,overactive;
Dnlg therapy
- From:
Chinese Journal of Geriatrics
2011;30(11):926-927
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the clinical therapeutic effect and safety of solifenacin suceinate in the treatment of overactive bladder symptom after benign prostatic hyperplasia (BPH)operation.MethodsAmong 115 patients receiving BPH surgery,58 cases were given solifenacin at bedtime 4 d after surgery for 20 d (treatment group),and 57 cases were given anisodamine after surgery (control group).The urination of patients before and after pulling out catheter were observed,and urodynamic examination,international prostatic symptoms score (IPSS) and overactive bladder symptom score (OABSS) were used to evaluate urination status.ResultsIn treatment group,IPSS and OABSS decreased from 28.3 to 11.3 score and from (14.2±1.2) to (2.9±0.7) score before and after treatment,respectively (P＜0.01).In control group,IPSS and OABSS decreased from 27.3 to 11.8 score (P＜0.01) and from (14.2±1.6) to (11.3±1.1) score before and after treatment,respectively (P＞0.05).ConclusionsThe proper use of solifenacin after prostate operation may release bladder distress and facilitate rehabilitation in patients with overactive bladder symptom.
