Clinical observation on Songlingxuemaikang combined with losartan in treatment of female menopausal bypertension
10.3760/cma.j.issn.1008-6706.2011.24.007
- VernacularTitle:松龄血脉康联合氯沙坦治疗女性更年期高血压
- Author:
Lei JIN
;
Li YAN
- Publication Type:Journal Article
- Keywords:
Menopausal syndrome;
Hypertension;
Female;
Songlingxuemaikang;
Losartan
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(24):3328-3330
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the effect of Songlingxuemaikang combined with losartan on the blood pressure and quality of life in female patients with menopausal hypertension.Methods87 female patients with menopausal hypertension were randomly divided into combined group (Songlingxuemaikang combined with losartan group,44 cases) and the control group(losartan alone,43 cases).Before and after treatment the ambulatory blood pressure (ABMP) was monitored for 24h,and blood lipids and clinical symptoms were observed.ResultsAfter two months treatment,the blood pressure variability and nighttime blood pressure decrease rate of the combination group significantly reduced,and better than those of the control group( all P ＜0.05) ;The effective rate and efficiency rate of the combination group were 90.9％,63.6％ respectively,and was higher than 74.4％,39.5％ in the control group( x2 =4.15,5.06,all P ＜ 0.05 ).The clinical symptoms improving,total cholesterol ( TC ) reducing,density lipoprotein (LDL-C) lowing in the combination group was superior to the control group( all P ＜ 0.05).ConclusionSonglingxuemaikang combined with losartan in treatment of female patients with menopausal hypertension had a good antihypertensive effect,and could reduce blood pressure variability in menopausal women,improve the symptoms of menopause and lipid metabolism,incresse the quality of lfie of patients with menopausal hypertensive.
