Clinical observation of long-term combined drug therapy for benign prostatic hyperplasia

VernacularTitle:良性前列腺增生患者长期联合药物治疗的临床观察
Author: Xuhong LI ; Fei GAO
Publication Type:Journal Article
Keywords: Prostatic hyperplasia; Drug therapy
From: Chinese Journal of Geriatrics 2011;30(11):928-929
CountryChina
Language:Chinese
Abstract: ObjectiveTo observe the curative effect of finasteride combined with terazosin on benign prostatic hyperplasia (BPH).Methods53 elderly patients with BPH continuously received finasteride (5 mg daily) and terazosin (2 mg daily) in our hospital from June 2002 to December 2010.The rating of international prostate symtom score (IPSS),nocturia,prostate volume and bladder residual urine were recorded before and 2 and 5 years after treatment.ResultsThe IPSS,nocturia,prostate volume,and bladder residual urine were better after treatment than before treatment (P＜ 0.05).The rating of IPSS,nocturia and prostate volume after 5 years of treatment also improved than after 2 years treatment (P＜0.05),but there was no difference in bladder residual urine between 5 years and 2 years of treatment.ConclusionsLong-term use finasteride combined with terazosin for treatment of BPH is effective with little side effects.