The relationship between the expression of bFGF in gastric cancer and precancerous lesions
10.3760/cma.j.issn.1008-6706.2011.23.012
- VernacularTitle:碱性成纤维细胞生长因子在胃癌及癌前病变组织中的表达
- Author:
Yaping HUANG
;
Haiying YU
;
Lingyun ZHANG
;
Qingru ZHU
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Fibroblast growth factor-2
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(23):3190-3192
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship of bFGF in the pathogenesis of gastric cancer.Methods The expression of bFGF was determined by immunohistochemical method in 130 gastric specimens including 30 cases of chronic superficial gastritis,30 cases of intestinal metaplasia,30 cases of dysplasia and 40 cases of gastric carcinomas.Results In control group with chronic superficial gastritis,precancerous group,and gastric carcinoma group,the expression level of bFGF had a increasing tendency(P ＜ 0.05).Conclusion The expression of bFGF was up-regulated in the carcinogenesis of gastric carcinoma.
