A correlation between benign prostate hyperplasia and atherosclerosis
10.3760/cma.j.issn.0254-9026.2011.11.006
- VernacularTitle:良性前列腺增生与动脉粥样硬化的关系
- Author:
Lu GAO
;
Mingzhao QIN
- Publication Type:Journal Article
- Keywords:
Prostatic hyperplasia;
Atherosclerosis
- From:Chinese Journal of Geriatrics
2011;30(11):919-920
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the correlation between benign prostate hyperplasia (BPH) and atherosclerosis (AS).Methods 95 cases were divided into two groups based on prostate volume (PV):24 cases with non-BPH (PV≤20 ml) and 71 cases with BPH (PV＞20 ml).Carotid intinal medial thickness (IMT) was determined by high resolution color Doppler sonography.ResultsLevels of triglyeeride (TG),hypersensitive C reactive protein (hs-CRP),ln fasting insulin [ln (FINS)],ln insulin resistance index [ln (HO)MA-IR)] and IMT in BPH group were significantly higher than in non-BPHgroup.The morbidity rate of coronary heart disease and cerebral arteriosclerosis in the BPH group enhanced as compared with non-BPH group.PV were positively correlated with ln(FINS),ln(HOMA-IR),TG and high density lipoprotein (HDL-C).Conclusions BPH is closely correlated with AS and their co-pathogenesis might be insulin resistance,inflammatory reaction and endothelial dysfunction.
