Applications of Different Insulin Therapies on type 2 diabetic patients in Fasting State
10.3760/cma.j.issn.1008-6706.2011.22.008
- VernacularTitle:不同胰岛素治疗方法用于2型糖尿病禁食患者效果观察
- Author:
Jianming YANG
;
Xiulan ZOU
;
Weimin ZHAO
;
Yanqun LIU
;
Wen WANG
;
Jun ZHENG
;
Jun YANG
;
Xuan XIA
;
Ping YU
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus;
Fasting;
Insulin pump;
Insulin glargine;
Hypoglycemia
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(22):3039-3040
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the status of diabetes in fasting state on different therapies.Methods 244 type 2 diabetic patients were divided into four groups according to different insulins:60 for insulin pump group(A),64 cases for insulin glargine group(B),59 cases for microinjection pump group(C),61 cases for isophane insulin suspension group.Then the time when blood glucose was up to standard,the usage of insulin and the rate of hypoglycemia were abserved.Results A group was(2.89 ± 1.32)d on the time when blood glucose was up to standard,B group was(3.14 ±1.25)d,C group was(4.91 ±2.81)d and D group was(5.62 ±2.52)d.There were significant differences between A and other groups( P < 0.05 ) on time.There were significant differences between B and C group,B and D group,but there was no difference between C and D group.A group was(30.61 ±2.21) IU/don the usage of insulin,B group was ( 31.12 ± 3.38 ) IU/d,C group was ( 42.25 ± 4.01 ) IU/d and D group was (44.31 ±3.22)IU/d.There were significant differences between A and C group,A and D group,B and C group,B and D group(P <0.05)on usage of insulin,but there were no differences between A and B group,C and D group.A group was 3.3% on the rate of hypoglycemia,B group was 4.7%,C group was 15.2% and D group was 16.4%.There were significant differences between A and C group,A and D group,B and C group,B and D group ( all P < 0.05 ) on usage of insulin,but there were no differences between A and B group,C and D group.Conclusion Compared to other insulin therapies,insulin pump had obviously superiority,which could be generalized to diabetics in fasting state.