The value of MR diffusion weighted imaging in differentiating benign and malignant lesions of prostate
10.3760/cma.i.issn.1673-4904.2011.32.011
- VernacularTitle:磁共振弥散加权成像在鉴别前列腺良、恶性肿瘤中的价值
- Author:
Wei LI
;
Wansheng LONG
;
Xuemao LUO
;
Manqiong CHEN
;
Yong LAN
;
Yigai HE
- Publication Type:Journal Article
- Keywords:
Prostatic neoplasms;
Prostatic hyperplasia;
Diffusion magnetic resonance imaging
- From:
Chinese Journal of Postgraduates of Medicine
2011;34(32):28-31
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the value of MR diffusion weighted imaging(DWI)and apparent diffusion coefficient(ADC)in differentiating benign and malignant lesions of prostate.Methods Twenty-two patients with prostate cancer and 17 patients with benign prostatic hyperplasia confirmed by pathology or biopsy,and 20 healthy volunteers were underwent prostate plain MRI,DWI and enhanced MRI,and measuring the value of ADC in the regions of interest in the workstation,and the ADC values of prostate cancer,benign prostatic hyperplasia,normal prostate were analyzed statistically.Results The ADC of prostate cancer,benign prostatic hyperplasia,normal prostate in central gland and peripheral zone were 1.08 ±0.23,1.43 ±0.27,1.51 ±0.26 and 1.26 ±0.47,1.72 ±0.40,1.75 ± 0.28,respectively,the ADC of prostate cancer was significantly lower than that of benign prostatic hyperplasia and normal prostate,and there was significant difference(P＜ 0.05),but there was no significant difference between benign prostatic hyperplasia and normal prostate(P ＞0.05).Looking the ADC was 1.30 and 1.60 in central gland and peripheral zone as the threshold to distinguish benign and malignant lesions of prostate,had high sensitivity and specificity.Conclusion The application of DWI combined with ADC,has improved the capability of diagnosis and differential diagnosis in benign and malignant lesions of prostate greatly.
