A comparison and significance of plasma riboflavin levels in patients with esophageal squamous cell carcinoma versus Linzhou healthy migrants in Changzhi of Shanxi
10.3760/cma.j.issn.0578-1426.2011.12.014
- VernacularTitle:山西长治地区健康林州移民及食管鳞癌患者血浆核黄素水平的比较及其意义
- Author:
Aifang JI
;
Wu WEI
;
Jinsheng WANG
;
Zibai WEI
;
Changhong LIAN
;
Jianzhou YANG
;
Li ZHAO
;
Liang MA
;
Li MA
;
Xiaoqi QIN
;
Xiaofeng HE
;
Lidong WANG
- Publication Type:Journal Article
- Keywords:
Riboflavin;
Esophageal neoplasms;
Enzyme-linked immunosorbent assay;
Linzhou immigrants
- From:
Chinese Journal of Internal Medicine
2011;50(12):1048-1050
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo study the relationship between plasma riboflavin levels and esophageal squamous cell carcinoma.Methods We detected and compared plasma concentrations of riboflavin in patients with esophageal squamous cell carcinoma (ESCC) and immigrants of Linzhou living in Changzhi.Plasma riboflavin levels were quantified in 445 ESCC patients,689 healthy control subjects and 347 immigrants of Linzhou living in Changzhi by using enzyme-linked immunosorbent assay.ResultsThe plasma riboflavin levels in patients with ESCC were significantly lower than those in the healthy controls and immigrants of Linzhou living in Changzhi [ (731.69 ± 330.67 ) μg/L vs ( 1090.43 ± 445.08 ) μg/L,(731.69 ± 330.67) μg/L vs ( 897.58 ± 177.78) μg/L,respectively,all P ＜ 0.05 ],and the plasma riboflavin levels of the healthy controls were higher than those in the immigrants of Linzhou living in Changzhi (P ＜ 0.05).ConclusionPatients with ESCC have decreased plasma riboflavin levels as compared with the healthy controls and immigrants of Linzhou living in Changzhi,there exists a lack of riboflavin in ESCC patients,but the specific mechanism needs further study.
