Zinc on cell proliferation and oifferentiation
10.3760/cma.j.issn.1673-4181.2011.05.015
- VernacularTitle:锌对细胞增殖、分化的影响
- Author:
Yang LV
;
Zhao LV
;
Jinghai LV
;
Jingying ZHANG
- Publication Type:Journal Article
- Keywords:
Zinc;
Cell cycle;
Signal transduction
- From:
International Journal of Biomedical Engineering
2011;34(5):318-320
- CountryChina
- Language:Chinese
-
Abstract:
Zinc is essential for cell proliferation and differentiation,especially for the regulation of DNA synthesis and mitosis.On the molecular level,it is a structural constituent of a great number of proteins including enzymes of cellular signaling pathways and transcription factors.Zinc can modulate cellular signal recognition,second messenger metabolism,protein kinase and protein phosphatase activities.It may stimulate or inhibit activities of transcription factors,and it may as well be used as a second messenger involved in cell signaling regulation.
