Effect of postoperative intravenous analgegia using dezocine on uterine contraction-induced pain after cesarean section
10.3760/cma.j.issn.1008-6315.2011.11.030
- VernacularTitle:地佐辛静脉用药对剖宫产产妇术后宫缩痛的影响
- Author:
Aibing ZHU
;
Mingkun SHEN
;
Zhiyong XU
- Publication Type:Journal Article
- Keywords:
Dezocine;
Uterine contraction-induced pain;
Cesarean section;
Tramadol;
Patientcontrolled intravenous analgesia
- From:
Clinical Medicine of China
2011;27(11):1207-1209
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of postoperative patient-controlled intravenous analgegia.using dezocine on uterine contraction-induced pain after cesarean section.Methods Sixty patients undergoing cesarean section were randomly divided into two groups with 30 cases each.Group D received patient-controlled intravenous analgesia(PCIA)with dezocine and tramadol.Group T received PCIA with tramadol.Ten minutes before completion of the operation,loading dose was given:in group D intravenous dezocine 0.1 mg/kg,in group T intravenous tramadol 2 mg/kg.Visual analogue scale(VAS)of wound pain and uterine contraction-induced pain,adverse effects were recorded at 4,8,16 and 24 h during analgesia.Results There was no siguiciant difference on VAS of wound pain between the two groups(P > 0.05).The VASs of uterine contraction-induced pain at the4,8,6 and 24th hour after surgery were(1.53 ±0.37),(2.28 ±0.15),(2.43 +0.56)and (2.01 ±0.64)respectively in Group D,which were significantly lower than those of(4.73 +0.43),(5.86 ±0.35),(5.83 ± 0.27)and(4.18 ± 0.53)in Group T(Ps < 0.05).Ramsay sedation scores were(3.97 ±1.41)and(3.12 ±0.06)at the 4 and 8 h,which were significantly lower than those of(1.12 ±0.49)and (1.09 ±0.73)in Group D(Ps <0.01)).However,there was no significant difference between the two groups in adverse effect(P > 0.05).Conclusion Intravenous patient-controlled analgesia with dezocine composite tramadol is not only effective for wound pain scores,but also can suppress uterine contraction-induced pain with less adverse effect in patients underwent cesarean section.