Clinical and etiological characteristics of the ventilator-associated pneumonia in newborns

VernacularTitle:新生儿呼吸机相关性肺炎的临床特点及病原菌分析
Author: Jidong LAI ; Changan OUYANG ; Xinzhu LIN ; Jianning WU
Publication Type:Journal Article
Keywords: Newborns; Ventilator-associated pneumonia; Pathogens
From: Clinical Medicine of China 2011;27(11):1210-1213
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical and etiologic characteristics and drug-resistance features of ventilator-associated pneumonia(VAP)in neonatal intensive care unit.Methods A retrospective study was conducted in 712 newborns with VAP who were admitted to the NICU from January 2007 to December 2010 and had received mechanical ventilation.The pathogenic bacteria spectrum of hospital infection were statistically analyzed.Results VAP was occurred in 69 out of 712 newborns with mechanical ventilation (incidence rate of 9.7％).The top four pathogens were saccharomyces albicans(39.2％),stenotrophomonas maltophilia(20.3％),staphylococcus epidermidis(13.5％)and klebsiella pneumoniae(9.5％),respectively.Conclusion Implementing strict measures to control the nosocomial infection can significantly reduce the incidence of VAP.Saccharomyces albicans,stenotrophomonas maltophilia,staphylococcus epidermidis and klebsiella pneumoniae were the pathogens most commonly involved.